CHOLESTO-LESS

Recommended Dose: Adults: Take 2 soft-gel capsules once per day with food and water at any mealtime

Duration Of Use: Consult a health care practitioner for continuous use beyond 24 weeks.

Do not use if you are pregnant, breastfeeding, or plan to become pregnant. Consult a health practitioner prior to use if you are taking medications, particularly, blood pressure medications, hydroxymethylglutaryl (HMG) CoA reductase lipid lowering drugs (statins), cyclosporine, anti-diabetic drugs, and/or blood thinners. Consult a health care practitioner prior to use if you have liver or kidney disease or have received an organ transplant.

Discontinue use and consult a health care practitioner if you experience muscle pain, tenderness and/or weakness, if symptoms persist or worsen, or if new symptoms develop.

Consult a health care practitioner prior to use if you have had recent surgery or have upcoming surgery. Keep out of reach of children.

Plant Sterol Esters (90% combined beta-sitosterol, campesterol, stigmasterol)

• Plant Sterol Esters look similar in structure to cholesterol, so they compete with and block about 50% of cholesterol from food and bile from being absorbed². This competitive action reduces LDL “bad” cholesterol and total cholesterol by about 10%, without reducing HDL “good” cholesterol in the body.
• Even a healthy diet does not provide enough Plant Sterol Esters to lower cholesterol, so supplementation is necessary to achieve adequate cholesterol-lowering doses².

Red Yeast Rice (Monascus purpurea – fermented Oryza sativa, Monascus purpurea – whole)

• Works in a similar way to cholesterol-lowering medications, called statins, but with a lower risk of side effects³.
• Inhibits the production of cholesterol in the liver, thereby lowering levels of total cholesterol by about 10% and LDL “bad” cholesterol by about 17%.
• Significantly decreases the occurrence of both fatal and non-fatal cardiac events⁴.

Ubiquinol (Active CoQ10) as Kaneka Q+

• Kaneka Q+ Ubiquinol is an all-natural yeast-fermented form of CoQ10 that is more well-absorbed and more readily utilized by the body than conventional inactive ubiquinone CoQ¹⁰.
• Powerful antioxidant that helps to heal damage to blood vessels caused by high cholesterol⁵.
• Improves both blood pressure and HDL “good” cholesterol levels, and reduces total cholesterol levels, thereby reducing the risk of heart disease^5,6.

Each Soft-Gel Contains:

Non-Medicinal Ingredients: Fish Gelatin Shell (fish gelatin, glycerin, purified water, carob powder), organic extra virgin olive oil, sunflower lecithin, mixed tocopherols concentrate)

Priority Allergens: This product contains fish.

Healthology does not use genetically modified ingredients. All ingredients are NON-GMO / GMO FREE.

• Cholesterol-lowering foods: Follow a high-fibre diet comprised of vegetables, fruits, fish, lean poultry, legumes, whole grains, nuts and olive oil⁷.
• Foods to avoid
  • Trans fats: These human-made fats are not naturally occurring and are harmful to the body. They are found in many packaged and fried foods and are the biggest culprit for increasing bad cholesterol and decreasing good cholesterol. Trans fats should be completely avoided in the diet.
  • Saturated fats: These are naturally occurring fats that are healthy at low levels but contribute to high cholesterol when eaten in high amounts. They are found in foods like red meat, dairy, coconut, avocado, and nuts. Try to keep saturated fats to a maximum of 6% of your daily calories, which would be about 13g per day for a standard 2000kcal diet⁸.
  • Sugars: Studies show that a higher intake of added sugar is associated with increased total cholesterol and LDL “bad” cholesterol, and increased risk of heart disease⁹. We should keep sugar in the diet as low as possible, with 25g being our daily maximum. Reading nutrition labels and avoiding sugary beverages and snacks is the best way to minimize sugar intake.
  • Foods containing cholesterol can be eaten in moderate amounts. Eggs, for example, are a healthy source of nutrients and protein, and it is recommended that we eat a maximum of 7 eggs weekly to maintain healthy cholesterol levels.
• Maintain a healthy weight: Regular exercise and a healthy diet are important to maintaining a healthy weight, which is directly correlated with improving cholesterol levels.
• Physical activity: Moderate intensity aerobic exercise for at least 150 minutes per week is the best type of exercise for improving HDL “good” cholesterol and reducing total and LDL “bad” and cholesterol levels¹⁰.
• Quit smoking: Smoking is a major risk factor the development of heart disease, and when combined with high cholesterol it presents an even greater risk for heart disease than either risk factor alone¹¹.
• Lab testing: A cholesterol panel should be monitored as part of your annual lab work, with a baseline level established as early as 18 years of age.

At ideal levels, cholesterol allows our body to function in a healthy way. However, many diets contain far too many foods that increase our cholesterol levels above what our bodies can use. Excess cholesterol can build up in our blood vessels, blocking oxygen from reaching our organs and causing damage to the body.

1. Elshourbagy NA, Meyers HV, Abdel-Meguid SS. Cholesterol: the good, the bad, and the ugly – therapeutic targets for the treatment of dyslipidemia. Med PrincPract. 2014;23(2):99–111.
2. Cabral CE, Klein MRST. Phytosterols in the treatment of hypercholesterolemia and prevention of cardiovascular diseases. Arq Bras Cardiol. 2017;109(5):475–482.
3. Klimek M, Wang S, Ogunkanmi A. Safety and efficacy of red yeast rice (Monascuspurpureus) as an alternative therapy for hyperlipidemia. P T. 2009;34(6):313–327.
4. Lu Z, Kou W, Du B, et al. Effect of Xuezhikang, an extract from red yeast Chinese rice, on coronary events in a Chinese population with previous myocardial infarction. Am J Cardiol. 2008;101(12):1689–1693.
5. Mohseni M, Vafa MR, Hajimiresmail SJ, et al. Effects of coenzyme q10 supplementation on serum lipoproteins, plasma fibrinogen, and blood pressure in patients with hyperlipidemia and myocardial infarction. Iran Red Crescent Med J. 2014;16(10):e16433.
6. Jorat MV, Tabrizi R, Mirhosseini N, et al. The effects of coenzyme Q10 supplementation on lipid profiles among patients with coronary artery disease: a systematic review and meta-analysis of randomized controlled trials. Lipids Health Dis. 2018;17(1):230.
7. Nordmann AJ, Suter-Zimmermann K, Bucher HC, Shai I, Tuttle KR, Estruch R et al. Meta-analysis comparing Mediterranean to low-fat diets for modification of cardiovascular risk factors. Am J Med 2011; 124(9): 841-851.
8. Mustad VA, Etherton TD, Cooper AD, et al. Reducing saturated fat intake is associated with increased levels of LDL receptors on mononuclear cells in healthy men and women. J Lipid Res. 1997;38(3):459–468.
9. Welsh JA, Sharma A, Abramson JL, Vaccarino V, Gillespie C, Vos MB. Caloric sweetener consumption and dyslipidemia among US adults. JAMA. 2010;303(15):1490–1497.
10. Mann S, Beedie C, Jimenez A. Differential effects of aerobic exercise, resistance training and combined exercise modalities on cholesterol and the lipid profile: review, synthesis and recommendations. Sports Med. 2014;44(2):211–221.
11. Jain RB, Ducatman A. Associations between smoking and lipid/lipoprotein concentrations among US adults aged ≥20 years. J Circ Biomark. 2018;7:1849454418779310.